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Science, Vol 306, Issue 5696, 595 , 22 October 2004
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[DOI: 10.1126/science.306.5696.595a]

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NATIONAL INSTITUTES OF HEALTH:
Male Sweep of New Award Raises Questions of Bias

Jeffrey Mervis

Where are the women? That's what some scientists are asking after the National Institutes of Health (NIH) picked nine men to receive the inaugural Director's Pioneer Award for innovative research (Science, 8 October, p. 220).

The 5-year, $500,000-a-year awards are part of NIH's "roadmap" for increasing the payoff from the agency's $28 billion budget, and Director Elias Zerhouni has compared the winners to famed U.S. explorers Merriweather Lewis and William Clark for their willingness "to explore uncharted territory." Within hours of the 29 September announcement, however, some researchers had begun to bristle at the gender imbalance in that first class of biomedical pioneers.

"It sends a message to women researchers that they are not on an even playing field," wrote Elizabeth Ivey, president of the Association for Women in Science, in a 1 October letter to Zerhouni. "I hope that you [will] make an effort to correct such a perception." The American Society for Cell Biology, in a 15 October letter to Zerhouni, commended him for creating the prize but lamented its "demoralizing effect" on the community. Critics noted that men constituted 94% (60 of 64) of the reviewers tapped to help winnow down some 1300 applications for the award and seven of the eight outside scientists on the final review panel, which grilled applicants for an hour before settling on the winners.

NIH officials estimate that women made up about 20% of the Pioneer applicants. But only about 13% of the 240 who made it through the first cut were women, and only two of the 21 finalists. (In contrast, about 25% of the applicants for NIH's bread-and-butter R01 awards to individual investigators are women, and their success rate is within a percentage point of that of their male counterparts.) "With any elite award, there are so many deserving candidates that it's easy to choose only men," says Stanford University neuroscientist Ben Barres, who says he was "outraged" by the gender imbalance. "I actually think it's more a matter of neglect than of sexism."

Figure 1 Men at work. Nine men won the first NIH Director's Pioneer Awards, chosen by panels that included few women.

SOURCE: NIH

The gender of the final applicants did not come up during the discussion, says review panel member Judith Swain, professor of medicine at Stanford. Swain, who called the exercise "the most interesting review panel I've ever been involved in," says she saw no evidence of "active discrimination." But she concurs that the demographics of the reviewers and the winners lead to "a disturbing observation."

NIH officials are struggling to find the best way to respond to the charges of gender insensitivity. Stephen Straus, head of the National Center for Complementary and Alternative Medicine and team leader for the NIH-wide competition, told Science on the day of the awards that "we gave the gender issue a great deal of thought, but none of the women finalists came close to making the pay line." A week later, in the first of a series of e-mail exchanges with Barres, Straus remarked that the absence of women was "noted with some surprise" by senior NIH officials and that "we know we can do better" in subsequent rounds. In a later exchange, however, Straus wrote, "I don't believe that NIH can credibly discard its two-level peer review system when nine grants out of the many thousands awarded this year turn out differently than some might wish."

NIH is evaluating how it ran the Pioneer program--including how the award was publicized and the demographics of the applicants--before launching the next competition in January. A thorough review is essential, says Arthur Kleinman, a medical anthropologist at Harvard University and chair of the final review panel, who believes NIH needs to do more to reach several groups--minorities and social and behavioral scientists as well as women--not represented in the first batch of winners. "I agree that they need to be more sensitive to diversity," he says. "But at the same time, I think Zerhouni deserves a lot of credit for even trying something like this."

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Volume 306, Number 5696, Issue of 22 Oct 2004, p. 595.
Copyright © 2004 by The American Association for the Advancement of Science. All rights reserved.

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